基本信息
浏览量:134
职业迁徙
个人简介
Our research concerns the role and assembly of transition metal centers in metalloenzymes and metalloproteins. Metal centers constitute the active sites of at least one third of all enzymes and determining the assembly mechanism of metallocenters and the electronic and structural properties of metal centers that confer selective and specific catalytic activity present fascinating challenges to inorganic chemists. In our work we use a range of spectroscopic techniques to probe the characteristic properties of transition metal centers, i.e. color, paramagnetism, etc. These include electron paramagnetic resonance (EPR), resonance Raman, FTIR, and UV/visible/near-IR absorption and natural and magnetically induced circular dichroism (CD and MCD). We also collaborate with other groups for Mossbauer, electron-nuclear double resonance (ENDOR), X-ray absorption and X-ray crystallography studies of proteins prepared in our laboratory. The information content of these techniques is often complementary and leads to a detailed information concerning the electronic, magnetic, and structural properties of metal centers imbedded in a large polypeptide macromolecule. The goal is detailed molecular-level understanding of the mechanism of assembly and/or the role of the metal center(s) in catalysis, regulation or electron transfer.
研究兴趣
论文共 223 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Biographical Memoirs of Fellows of the Royal Society (2022)
Jonathan Przybyla-Toscano, Andrew Mclean,Tamanna Azam, Cyril Magno,Tiphaine Dhalleine,Jérémy Couturier,Frédéric Gaymard,Florence Vignols,Michael K. Johnson, Janneke Balk, Nicolas Rouhier
HAL (Le Centre pour la Communication Scientifique Directe) (2018)
引用0浏览0引用
0
0
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn