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Dr. Palena’s research focuses on the immunological targeting of drivers of tumor metastasis and resistance to therapy. Her recent studies on a novel tumor-associated antigen, the transcription factor brachyury, have led to the rapid translation of 3 cancer vaccine platforms targeting a driver of the epithelial-mesenchymal transition, a process associated with cancer progression, from basic discovery to Phase I and II clinical studies.
As the Head of the Immunoregulation Section, Dr. Palena continues to investigate innovative immunotherapeutic approaches that may be used in combination with other anti-neoplastic agents to generate anti-tumor immune responses that could alleviate metastatic disease in cancer patients.
As the Head of the Immunoregulation Section, Dr. Palena continues to investigate innovative immunotherapeutic approaches that may be used in combination with other anti-neoplastic agents to generate anti-tumor immune responses that could alleviate metastatic disease in cancer patients.
研究兴趣
论文共 179 篇作者统计合作学者相似作者
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Maria Del Mar Maldonado,Masafumi Iida, Maria Del Mar Gracia Hernandez, Loc Le,Renee N. Donahue,Claudia Palena,Jeffrey Schlom,Duane H. Hamilton
Cancer Researchno. 6_Supplement (2024): 4092-4092
Lucas A. Horn,Haiyan Qin, Masafumi Iida,Kristen Fousek, Shantel Angstadt,John W. Greiner,Jeffrey Schlom,Claudia Palena
Regular and Young Investigator Award Abstracts (2023)
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Jeffrey Schlom, Jacques Moisan,Claudia Palena,Kristen Fousek,Lucas A Horn, Andrew Bayliffe,Haiyan Qin,Shantel Angstadt,Madan Katragadda
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
Journal for ImmunoTherapy of Cancerno. Suppl 1 (2023)
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