The Role of Chemotherapy and Radiotherapy in Penile Cancer

Chemotherapy and radiation may be used in many instances in the management of penile cancer. Cytotoxic chemotherapy has been used as palliative treatment to prolong life and improve symptoms in metastatic inoperable penile cancer and more recently has moved forward in the therapeutic algorithm as an important perioperative treatment in high risk locally advanced node positive disease. Radiotherapy additionally has an important role in the treatment of the primary lesion and the lymphatic drainage. It is therefore important to involve oncologists early in the pathway of patient treatment and ensure multidisciplinary decision making.