The accuracy of p53 immunohistochemistry is impaired in endometrial cancer with a high mutation burden

Giovanni Aletti,Luigi Antonio De Vitis,Gabriella Schivardi,Caterina Fumagalli, Marianna Marzoli, Susanna Delfrati,Mariacristina Ghioni,Paola Rafaniello Raviele,Alessandra Rappa,Maria Teresa Achilarre,Alessia Aloisi,Annalisa Garbi,Gabriella Parma,Vanna Zanagnolo,Andrea Mariani,Angelo Maggioni,Massimo Barberis,Nicoletta Colombo,Francesco Multinu,Ilaria Betella

GYNECOLOGIC ONCOLOGY（2023）

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摘要

We compared the immunohistochemical expression of p53 and the mutational status of the TP53 gene in endometrial cancers (ECs) classified according to the WHO-endorsed molecular classification.

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关键词

p53 immunohistochemistry,endometrial cancer,high mutation burden

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