Supplemental Figure 4 from CD40 Signaling Drives Potent Cellular Immune Responses in Heterologous Cancer Vaccinations

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In this figure, the liver damage induced by heterologous, DC-based immune responses is illustrated. Mice were primed with dendritic cells and subjected to different booster immunizations consisting of variable combinations of anti-CD40, Poly I:C and peptide antigen. Liver damage was assessed via ALT measurements 24 and 72h after booste immunizations

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