Supplementary Figure 3 from Endoneurial Macrophages Induce Perineural Invasion of Pancreatic Cancer Cells by Secretion of GDNF and Activation of RET Tyrosine Kinase Receptor

PDF file - 178K, Scratch assays of MiaPaCa2 cells in the presence or absence of EMPhi-CM. (a) Representative pictures taken after 24 and 48 hours showing increased motility of cancer cells incubated with EMPhi-CM (lower row) relative to normal medium (DMEM- upper row). (b) Summary of the data showing statistically significant increase in cancer cell motility after incubation in EMPhi-CM compared to normal media (n=6, P<0.001).