Severe and fatal COVID-19 is characterised by increased circulating glucagon like peptide 1 and procalcitonin modulated by type 2 diabetes.

Olga Bloch, Perl Kobi,Ariel Ben Shimol,Assaf Rotmensh,Dana Kagansky,Dana Zelnik-Yovel,Gilad Ben Yehudah,Dror Cantrell,Micha J Rapoport

Diabetes/metabolism research and reviews（2023）

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摘要

The persistent joint increase of endogenous GLP-1 and PCT in severe and fatal COVID-19 suggests a role of concomitant bacterial infection in disease exacerbation. Early elevation of endogenous GLP-1 may serve as a new biomarker of COVID-19 severity and fatal outcome.

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关键词

COVID-19 severity,IL-6,diabetic,endogenous GLP-1 response,nondiabetic,procalcitonin

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