Long-Term Exposure to Nitrate and Trihalomethanes in Drinking Water and Prostate Cancer: A Multicase-Control Study in Spain (MCC-Spain).

Carolina Donat-Vargas,Manolis Kogevinas,Gemma Castaño-Vinyals,Beatriz Pérez-Gómez,Javier Llorca,Mercedes Vanaclocha-Espí,Guillermo Fernandez-Tardon,Laura Costas,Nuria Aragonés,Inés Gómez-Acebo,Victor Moreno,Marina Pollan,Cristina M Villanueva

Environmental health perspectives（2023）

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摘要

Findings suggest long-term waterborne ingested nitrate could be a risk factor of prostate cancer, particularly for aggressive tumors. High intakes of fiber, fruit/vegetables and vitamin C may lower this risk. Association with residential levels but not ingested chloroform/Br-THM may suggest inhalation and dermal routes could be relevant for prostate cancer. https://doi.org/10.1289/EHP11391.

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关键词

trihalomethanes,nitrate,prostate cancer,drinking water,long-term,mcc-spain

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