Measuring Serum Vedolizumab and Vedolizumab Antibodies: Comparison of Commercial Assays with the Vedolizumab Clinical Development Assay.

Niels Vande Casteele,Lili Yang,Iwona Dobler,Christian Agboton,Teresa McRorie Osborn,Ajit Suri,Dirk Lindner,Glennda M Smithson

Therapeutic drug monitoring（2023）

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摘要

All 5 commercial assays are suitable for VDZ therapeutic monitoring and ADA testing. However, the absolute values from the reference assays and the different commercial assays were not comparable, indicating that the same assay must be used for repeated monitoring of VDZ serum concentrations.

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vedolizumab, assay, ulcerative colitis, Crohn's disease

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