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The risks of cancer in older women with BRCA pathogenic variants: How far have we come?

Kelly A. Metcalfe,Jacek Gronwald,Nadine M. Tung,Jeanna M. McCuaig,Andrea Eisen,Christine Elser,William D. Foulkes,Susan L. Neuhausen,Leigha Senter,Pal Moller,Louise Bordeleau,Robert Fruscio,Lea Velsher,Dana Zakalik,Olufunmilayo I. Olopade,Charis Eng,Tuya Pal,Carey A. Cullinane,Fergus J. Couch,Joanne Kotsopoulos,Ping Sun,Jan Lubinski,Steven A. Narod

Cancer（2023）

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摘要
Women with a BRCA1 or BRCA2 pathogenic variant have a high risk of cancer between the ages of 50 and 75 years and should be counselled appropriately.
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关键词
BRCA1,BRCA2,breast neoplasm,fallopian tube neoplasm,ovarian neoplasm
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