Role of SAMITAL in the Prevention and Treatment of Chemo-Radiotherapy-Induced Oral Mucositis in Head and Neck Carcinoma: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Clinical Trial (ROSAM).

Elena Fasanaro,Paola Del Bianco,Elena Groff,Antonella Riva,Giovanna Petrangolini,Fabio Busato, Paola Stritoni,Giovanni Scarzello,Lucio Loreggian,Gian Luca De Salvo

Cancers（2022）

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摘要

SAMITAL did not significantly reduce the incidence of severe mucositis in all studied populations. However, the lower rate of mucositis, together with a significantly better quality of life, suggested that a clinical benefit existed. This trial is registered with the EU Clinical Trials Register database, number 2012-002046-20, and with ClinicalTrials.gov, NCT01941992.

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关键词

SAMITAL,botanical drug,chemo-radiotherapy,head and neck squamous cell carcinoma,oral mucositis,quality of life

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