MTHFR c.665C>T guided fluoropyrimidine therapy in cancer: gender-dependent effect on dose requirements.
Drug metabolism and personalized therapy(2022)
摘要
c.665C>T polymorphism was associated with fluoropyrimidine dose reduction in female cancer patients. This gender* interaction merits further investigation.
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关键词
MTHFR
,
TYMS
,chemotherapy response,fluoropyrimidine,gender interaction
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