Thyroid-like follicular renal cell carcinoma with sarcomatoid differentiation and an aggressive clinical course: a case report confirming the presence of the EWSR1::PATZ1 fusion gene

Thyroid-like follicular renal cell carcinoma (TFRCC) is rare, with <50 cases reported in the litterature. Recently, Al-Obaidy et al. described recurrent EWSR1::PATZ1 fusions in TFRCC, supporting its classification as an independent entity . We report herein a diagnostically challenging case of TFRCC with sarcomatoid differentiation, aggressive clinical course and presence of an EWSR1::PATZ1 fusion.