Survival Outcomes From a Cumulative Analysis of Worldwide Observational Studies on Sequential Use of New Agents in Metastatic Castration-Resistant Prostate Cancer.

Orazio Caffo,Michel Wissing,Diletta Bianchini,Andries Bergman,Frederik B Thomsen,Sebastian Schmid,Evan Y Yu,Evangelos Bournakis,Avishay Sella,Vittorina Zagonel,Ugo De Giorgi,Marcello Tucci,Hans Gelderblom,Luca Galli,Giovanni Pappagallo,Emilio Bria,Isabella Sperduti,Stephane Oudard

Clinical Genitourinary Cancer（2020）

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摘要

Our findings suggest that the sequential use of NAs with different mechanisms of action improves cumOS regardless of the order in which they are administered, thus supporting the hypothesis of cross-resistance between the 2 NHAs.

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关键词

Androgen-receptor targeting agents,Chemotherapy,Second-line,Sequencing,Third-line

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