Nationwide epidemiology of early-onset sepsis in Israel 2010-2015, time to re-evaluate empiric treatment.

Daniel Glikman, Nitzan Curiel,Aharona Glatman-Freedman,Orli Megged,Ilan Youngster,Ronella Marom, Karen Lavie,Tatiana Smolkin,Mara Troitzky,Michal Stein

Acta paediatrica (Oslo, Norway : 1992)（2019）

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摘要

In this nationwide study, EOS was caused predominantly by Gram-negatives, with high gentamicin resistance and ESBL phenotype rates, without identifiable resistance risk factors. As EOS is life-threatening, modification of empiric therapy for amikacin-based regimens should be considered, mainly in preterms. This article is protected by copyright. All rights reserved.

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关键词

Antimicrobial resistance rates,Early-onset neonatal sepsis,Empiric antimicrobial therapy,Gram-negative pathogens,preterm neonates

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