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个人简介
Dr. Yan is a leader in mitochondrial research in Alzheimer’s disease (AD). She was the first to report amyloid pathology in mitochondria. She was the first identified the specific cellular targets (RAGE, receptor for advanced glycation end product and mitochondrial proteins-mediated mitochondrial and neuronal degeneration. She has developed several novel transgenic human diseases mouse model relevant to aging, diabetes, AD to test the role of cellular cofactors and mitochondrial protein in genotoxin- and amyloid-mediated mitochondrial perturbation and neurodegeneration.
Her research has been repeatedly highlighted in world-wide leading journals, including Nature, Nature Medicine, Science, Brain, and PNAS. Her research has won multiple awards, including the Dolph C. Simons Award in Biomedical Science, the NIH MERIT Award from the National Institute on Aging “ in recognition of sustained contribution to aging and leadership and commitment to the field” and the Zenith Fellow Award from Alzheimer’s Association that is among the most prestigious in Alzheimer’s research worldwide. She currents sits on the editorial board for several prominent research publications, including Current Alzheimer’s Research and Journal of Alzheimer’s Disease.
Her research has been repeatedly highlighted in world-wide leading journals, including Nature, Nature Medicine, Science, Brain, and PNAS. Her research has won multiple awards, including the Dolph C. Simons Award in Biomedical Science, the NIH MERIT Award from the National Institute on Aging “ in recognition of sustained contribution to aging and leadership and commitment to the field” and the Zenith Fellow Award from Alzheimer’s Association that is among the most prestigious in Alzheimer’s research worldwide. She currents sits on the editorial board for several prominent research publications, including Current Alzheimer’s Research and Journal of Alzheimer’s Disease.
研究兴趣
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Sourav Samanta,Firoz Akhter,Anuradha Roy,Doris Chen, Benjamin Turner,Yongfu Wang,Nicolina Clemente,Chunyu Wang,Russell Howard Swerdlow,Kevin P Battaile,Scott Lovell, Shi Fang Yan,
Brain : a journal of neurologyno. 5 (2024): 1710-1725
bioRxiv : the preprint server for biologyno. 5 (2024)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Oxford University Press eBookspp.C23S1-C23P328, (2023)
Free radical biology & medicine (2021): 429-438
biorxiv(2020)
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